The cause of juvenile diabetes is insulin
Camillo Ricordi, international renowned researcher at the University of Miami and the ISMETT of Palermo, is a sponsor of one of two studies published May 12 on the journal Nature. He explained how was conducted to identify the cause of the most serious diabetes: Type 1 diabetes or juvenile diabetes, which affects the United States on a young 400-500. The existence of a genetic predisposition could not, so far, to explain the onset of the disease.
Camillo Ricordi, internationally renowned researcher at the University of Miami and the ISMETT of Palermo, is a sponsor of one of two studies published May 12 on the journal Nature. He explained how was conducted to identify the cause of the most serious diabetes: Type 1 diabetes or juvenile diabetes, which affects the United States on a young 400-500. The existence of a genetic predisposition could not, so far, to explain the onset of the disease. Researchers at the University of Miami, Harvard (Boston) and Minnesota have understood that the cells of the immune system, for reasons as yet unknown, attacked a portion of the insulin molecule and kill cells that produce ( the beta cells in the pancreas). The body was then stripped of the hormone vital for the control of the metabolism of sugars and for the regulation of blood sugar, and those who fall sick are forced to insulin injections or a new transplant beta cells (Ricordi method) . The cause of the disease is therefore an action of "self", concerning the attack only the insulin made by the patient and not synthetic or foreign. In the second study, mice destined to become diabetic, have been genetically modified so as to be unable to produce their own insulin, which is substituted by a biotech. Guinea pigs, which then grow up without their own insulin, remain to be free from diabetes and do not become ill. This fundamental breakthrough opens the way to new strategies for treatment and prevention
Camillo Ricordi, internationally renowned researcher at the University of Miami and the ISMETT of Palermo, is a sponsor of one of two studies published May 12 on the journal Nature. He explained how was conducted to identify the cause of the most serious diabetes: Type 1 diabetes or juvenile diabetes, which affects the United States on a young 400-500. The existence of a genetic predisposition could not, so far, to explain the onset of the disease. Researchers at the University of Miami, Harvard (Boston) and Minnesota have understood that the cells of the immune system, for reasons as yet unknown, attacked a portion of the insulin molecule and kill cells that produce ( the beta cells in the pancreas). The body was then stripped of the hormone vital for the control of the metabolism of sugars and for the regulation of blood sugar, and those who fall sick are forced to insulin injections or a new transplant beta cells (Ricordi method) . The cause of the disease is therefore an action of "self", concerning the attack only the insulin made by the patient and not synthetic or foreign. In the second study, mice destined to become diabetic, have been genetically modified so as to be unable to produce their own insulin, which is substituted by a biotech. Guinea pigs, which then grow up without their own insulin, remain to be free from diabetes and do not become ill. This fundamental breakthrough opens the way to new strategies for treatment and prevention
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